龙 勉 性 别 男 职 称 研究员 学 历 博士 地 址 北京北四环西路15号中国科学院力学研究所 邮 编 100080 电 话 (010) 62613540 传 真 (010) 62613540 电子邮件longmian@hotmail.com；mlong@imech.ac.cn 简 历 1980.9-1984.7 上海交通大学动力机械工程系 科学学士 1984.9-1987.7 重庆大学生物工程研究中心 硕士生提前攻博 1987.7-1990.7 重庆大学生物工程研究中心 工学博士 （中日联合培养） 1989.3-1990.3 日本群马大学工学部生物及化学工程系 联培博士 1990.7-1992.4 重庆大学生物工程研究中心 讲师 1992.4-1995.3 重庆大学生物工程研究中心（院） 副研究员 1995.3-2000.7 重庆大学生物工程研究（学）院 教授 1996.6-1999.8 美国佐治亚理工学院机械工程系 高访学者 2000.7-至今 中国科学院力学研究所 院"百人计划" 研究员, 博士生导师 2002.11-至今 国家杰出青年基金获得者 研究领域：细胞-分子生物力学；生物微系统；空间生物技术。 代表论著：1. Jun Huang, Juan Chen, Scott E. Chesla, Tadayuki Yago, Padmaja Mehta, Rodger P. McEver, Cheng Zhu, and Mian Long. Quantifying the effects of molecular orientation and length on two- dimensional receptor-ligand binding kinetics. J. Biol. Chem., Vol.279(43):44915-44923 2. Lü S.Q., and Long M. 2004. Forced extension of P-selectin construct using steered molecular dynamics. Chinese Science Bulletin, Vol. 49(1): 10-17. 3. Marshall B.T., Long M., Piper J.W., Yago T., McEver R.P., and Zhu C. Direct observation of catch bonds. Nature, Vol. 423: 190-193. 4. Song G.B., Wu W.Q., Long M., Wu Z.Z., Liu B.A., Wang B.C., and Cai S.X.2002. Investigation on the viscoelasticity of synchronous hepatocellular carcinoma cells. Colloids and Surfaces B: Biointerfaces, Vol. 24: 327-332. 5. Zhu C, Long M., Chesla S.E., and Bongrand P. 2002. Measuring receptor/ligand interaction at the single bond level: Experimental and interpretive issues. Ann. Biomed. Engi., Vol.30: 305-314. 6. Long M., Zhao H., Huang K.-S., and Zhu C. 2001. Kinetic measurements of cell surface E-selectin/carbohydrate ligand interactions. Ann. Biomed. Engi., Vol.29: 935-94. 7. Shao K.F., Wu Z.Z., Wang B.C., Long M., and Cai S.X. 2000. Effects of colchicines and cytochalasin D on the adhesion properties of the HCC onto the collagen IV/laminin coated surface. Colloids and Surfaces B: Biointerfaces, Vol. 19(1): 55-59 8. Wu Z.Z., Zhang G., Long M., Wang H.B., Song G.B., and Cai S.X. 2000. Comparison of the viscoelastic properties of normal hepatocytes and hepatocarcinoma cells under cytoskeletal perturbation. Biorheology, Vol. 37(4): 279-290. 9. Wang X., Wu Z.Z., Song G.B., Wang H.B., Long M., and Cai S.X. 1999．Effects of oxidative damage of membrane protein thiol groups on erythrocyte membrane viscoelasticity. Clin. Hemorheo. & Microcircul., Vol.21:137-146. 10. Long M., Goldsmith H.L., Tees D.F.J., and Zhu C. 1999. Probabilistic modeling of shear-induced formation and breakage of doublets cross-linked by receptor-ligand bonds. Biophys. J., Vol.76:1112-1128. 11. Long M., Wang H. B., Wu Z. Z., Wu Y. P., and Sakanishi A. 1994. Effect of electric field on erythrocyte sedimentation rate IV. Volume fraction dependence of human red cells in plasma. Biorheology, Vol.31, No.3:287-296. 12. Toyama Y., Long M., Dobashi T., Sakanishi A., Cerny L. C., and Oka S. 1990. Erythrocyte sedimentation rate VI. Comparison of deformability in hardened and intact erythrocytes. Reports on Progress in Polymer Physics in Japan, Vol.33:615-616. 13. Long M., Toyama Y., Dobashi T., Sakanishi A., Wu Y. P., and Oka S. 1990. Effect of electric field on erythrocyte sedimentation rate III. Volume fraction dependence in saline solution. Reports on Progress in Polymer Physics in Japan, Vol.33:623-626. 14. Long M., Toyama Y., Dobashi T., Sakanishi A., Wu Y. P., and Oka S. 1990. Effect of electric field on erythrocyte sedimentation rate I. Enhancement in saline solution. Biorheology, Vol.27, No.2:241-246. 15. Long M., Toyama Y., Dobashi T., Sakanishi A., Wu Y. P., and Oka S. 1990. Effect of electric field on erythrocyte sedimentation rate II.Dependence on electric current. Biorheology,Vol.27(5): 769-777.
