The effect of shock sterilization on marine Vibrio sp. is investigated by carrying out a bio-experiment based on a bubble-shockwave interaction. In the experiments, underwater shock waves with different strength and frequencies are produced by a high-voltage power supply in a cylindrical water chamber. The bio-experimental results show marine Vibrio sp. is completely inactivated in a short time by a 1.0-Hz electric discharge. However, a high sterilization effect requires a strong and high frequency of the bubble motion, and it also depends on the lifetime of the bubble. Subsequently, by an experiment with an air gap to prevent the underwater shock waves entering the cell suspension, it is found that the introduction of a strong shock pressure is not entirely required to obtain the effective sterilization. On the other hand, the direct effect of the sterilization by rebound shock wave resulting from the bubble-shock wave interaction is examined in the experiments. The results suggest that free radicals mainly contribute to killing marine bacteria, and direct mechanical effects of the bubble motion are not responsible. In addition, the creation of the OH radical is indirectly confirmed by measuring the H₂O₂concentration. Finally, the Herring equation is solved to investigate the condition of free radical generation when considering the effect of thermal conductivity at the bubble interface. As a result, the effective sterilization conditions based on the bubble-shock wave interaction are clearly obtained.

A theoretical model for estimating inactivation effects on marine Vibrio sp. is developed from the viewpoint of the chemical action of the OH radicals induced by interaction of bubbles with shock waves. It consists of a biological probability model for cell viability and a bubble dynamic model for its collapsing motion due to the shock pressures. The biological probability model is built by defining a sterilized space of the OH radicals. To determine the radius of the sterilized space, the Herring equation is solved in the bubble dynamic model in consideration of the effect of the heat conductivity and mass transportation. Furthermore, the pressure waveform of incident shock wave used in the model is obtained with the pressure measurement. On the other hand, a bio-experiment of marine Vibrio sp. is carried out using a high-voltage power supply in a cylindrical water chamber. Finally, the viability ratio of marine bacteria estimated by the theoretical model is examined under the experimental conditions of this study. In addition, we also discuss the influence of bubble initial size for predicting the inactivation effects.

为了研究轴对称体非定常空化的脉动特性,采用高速全流场显示技术和动态测力系统实验研究了绕半球型和平头轴对称体的非定常空化流场及其动力特性。实验在闭式水洞中进行,采用高速摄影的方法观察了在不同空化数下绕半球型和平头轴对称体的空穴形态,总结了在不同空化数下空泡形态的脉动特性;测量了轴对称体受到的阻力,并对阻力信号进行了时频分析,得到了轴对称体阻力在非定常空化阶段的时频特征。结果表明:空泡形态及其对应的动力特征随着空化数的变化存在明显的非定常特性,空化流场形态与动力特征频率存在高度的相关性。并且不同头型轴对称体的脉动特性存在明显的差异,半球型轴对称体空泡流动的脉动主要是空泡尾部的高频小脱落引起的,而平头轴对称体的空泡流脉动成分主要是大尺度的漩涡空泡团的周期性脱落,空化流场的低频特征频率与空泡的大断裂相对应。

为了研究轴对称体非定常空化的脉动特性,采用高速全流场显示技术和动态测力系统实验研究了绕半球型和平头轴对称体的非定常空化流场及其动力特性。实验在闭式水洞中进行,采用高速摄影的方法观察了在不同空化数下绕半球型和平头轴对称体的空穴形态,总结了在不同空化数下空泡形态的脉动特性;测量了轴对称体受到的阻力,并对阻力信号进行了时频分析,得到了轴对称体阻力在非定常空化阶段的时频特征。结果表明:空泡形态及其对应的动力特征随着空化数的变化存在明显的非定常特性,空化流场形态与动力特征频率存在高度的相关性。并且不同头型轴对称体的脉动特性存在明显的差异,半球型轴对称体空泡流动的脉动主要是空泡尾部的高频小脱落引起的,而平头轴对称体的空泡流脉动成分主要是大尺度的漩涡空泡团的周期性脱落,空化流场的低频特征频率与空泡的大断裂相对应。

针对航行体水下垂直发射出水载荷机理问题, 首先开展了典型工况全过程的数值模拟, 得到了航行体肩、尾空泡及表面压力的演化过程, 并与试验结果进行了对比验证. 在此基础上揭示了航行体肩部空泡溃灭的过程和机制, 进而提出了出水溃灭压力的物理模型, 探索了空泡厚度、水层厚度、声速等重要参数的影响, 讨论了试验溃灭压力相似律等相关问题.

针对航行体水下垂直发射出水载荷机理问题, 首先开展了典型工况全过程的数值模拟, 得到了航行体肩、尾空泡及表面压力的演化过程, 并与试验结果进行了对比验证. 在此基础上揭示了航行体肩部空泡溃灭的过程和机制, 进而提出了出水溃灭压力的物理模型, 探索了空泡厚度、水层厚度、声速等重要参数的影响, 讨论了试验溃灭压力相似律等相关问题.

When attempting to clean surfaces of dental root canals with laser-induced cavitation bubbles, the resulting cavitation oscillations are significantly prolonged due to friction on the cavity walls and other factors. Consequently, the collapses are less intense and the shock waves that are usually emitted following a bubble's collapse are diminished or not present at all. A new technique of synchronized laser-pulse delivery intended to enhance the emission of shock waves from collapsed bubbles in fluid-filled endodontic canals is reported. A laser beam deflection probe, a high-speed camera, and shadow photography were used to characterize the induced photoacoustic phenomena during synchronized delivery of Er:YAG laser pulses in a confined volume of water. A shock wave enhancing technique was employed which consists of delivering a second laser pulse at a delay with regard to the first cavitation bubble-forming laser pulse. Influence of the delay between the first and second laser pulses on the generation of pressure and shock waves during the first bubble's collapse was measured for different laser pulse energies and cavity volumes. Results show that the optimal delay between the two laser pulses is strongly correlated with the cavitation bubble's oscillation period. Under optimal synchronization conditions, the growth of the second cavitation bubble was observed to accelerate the collapse of the first cavitation bubble, leading to a violent collapse, during which shock waves are emitted. Additionally, shock waves created by the accelerated collapse of the primary cavitation bubble and as well of the accompanying smaller secondary bubbles near the cavity walls were observed. The reported phenomena may have applications in improved laser cleaning of surfaces during laser-assisted dental root canal treatments.

Flynn方程在引入泡内气体的压缩性修正后能够更好地描述超声波作用下液体内气泡的非线性振动。我们以此为基础通过数值分析得到了不同初始半径的气泡在同一声场中的振动位移时间图像和相轨迹，发现气泡的运动行为对其初始状态有很强的依赖关系，在频率为26.5 kHz，幅度为1.35 atm的声波作用下，初始半径小于1 μm的气泡作小幅受迫振动，大于200 μm的气泡作小幅准本征振动，不具备空化气泡特征。声场中的小气泡对声波强度变化的反应更为激烈，当增加声强度时，可将一定范围内的小幅受迫振动气泡转化为空化气泡，并且，当驱动声波压力幅值增加时，初始半径越小的气泡的最大位移增加幅度越大。驱动声波频率同样影响气泡的振动。随着声波频率的升高，空化气泡的初始半径取值区间越来越小，空化振荡也越来越弱。本文还通过高速摄影系统对换能器作用于未除气的自来水所引起的变化进行了实验研究，结果表明，超声波作用下液体内的气泡场是一个混合场，场内气泡尺寸呈一定的分布状态，不仅有空化气泡，还有毫米级的大气泡。气泡的运动行为直接影响空化效果。超声空化场是一个复杂的物理场，场内除了有气泡的振动外，还有气泡间的相互吸引、碰撞和结合。

Flynn方程在引入泡内气体的压缩性修正后能够更好地描述超声波作用下液体内气泡的非线性振动。我们以此为基础通过数值分析得到了不同初始半径的气泡在同一声场中的振动位移时间图像和相轨迹，发现气泡的运动行为对其初始状态有很强的依赖关系，在频率为26.5 kHz，幅度为1.35 atm的声波作用下，初始半径小于1 μm的气泡作小幅受迫振动，大于200 μm的气泡作小幅准本征振动，不具备空化气泡特征。声场中的小气泡对声波强度变化的反应更为激烈，当增加声强度时，可将一定范围内的小幅受迫振动气泡转化为空化气泡，并且，当驱动声波压力幅值增加时，初始半径越小的气泡的最大位移增加幅度越大。驱动声波频率同样影响气泡的振动。随着声波频率的升高，空化气泡的初始半径取值区间越来越小，空化振荡也越来越弱。本文还通过高速摄影系统对换能器作用于未除气的自来水所引起的变化进行了实验研究，结果表明，超声波作用下液体内的气泡场是一个混合场，场内气泡尺寸呈一定的分布状态，不仅有空化气泡，还有毫米级的大气泡。气泡的运动行为直接影响空化效果。超声空化场是一个复杂的物理场，场内除了有气泡的振动外，还有气泡间的相互吸引、碰撞和结合。

The immune and nervous systems share many features, including receptor and ligand expression, enabling efficient communication between the two. Accumulating evidence suggests that the communication is bidirectional, with the neural system regulating immune cell functions and vice versa. Steroid hormones from the hypothalamus-pituitary-adrenal gland axis are examples of systemic regulators for this communication. Neural reflexes describe regional regulation mechanisms that are a historically new concept that helps to explain how the neural and body systems including immune system communicate. Several recently identified neural reflexes, including the inflammatory reflex and gateway reflex, significantly impact the activation status of the immune system and are associated with inflammatory diseases and disorders. Either pro-inflammatory or anti-inflammatory effects can be elicited by these neural reflexes. On the other hand, the activities of immune cells during inflammation, for example the secretion of inflammatory mediators, can affect the functions of neuronal systems via neural reflexes and modulate biological outputs via specific neural pathways. In this review article, we discuss recent advances in the understanding of bidirectional neuro-immune interactions, with a particular focus on neural reflexes.

High-intensity focused ultrasound (HIFU) provides a potential noninvasive alternative to conventional therapies. We report our preliminary experience from clinical trials designed to evaluate the safety and feasibility of a novel, extracorporeal HIFU device for the treatment of liver and kidney tumours in a Western population. The extracorporeal, ultrasound-guided Model-JC Tumor Therapy System (HAIFU Technology Company, China) has been used to treat 30 patients according to four trial protocols. Patients with hepatic or renal tumours underwent a single therapeutic HIFU session under general anaesthesia. Magnetic resonance imaging 12 days after treatment provided assessment of response. The patients were subdivided into those followed up with further imaging alone or those undergoing surgical resection of their tumours, which enabled both radiological and histological assessment. HIFU exposure resulted in discrete zones of ablation in 25 of 27 evaluable patients (93%). Ablation of liver tumours was achieved more consistently than for kidney tumours (100 vs 67%, assessed radiologically). The adverse event profile was favourable when compared to more invasive techniques. HIFU treatment of liver and kidney tumours in a Western population is both safe and feasible. These findings have significant implications for future noninvasive image-guided tumour ablation.

With the development of nanotechnology, nanocarriers have been increasingly used for curative drug/gene delivery. Various nanocarriers are being introduced and assessed, such as polymer nanoparticles, liposomes, and micelles. As a novel theranostic system, nanocarriers hold great promise for ultrasound molecular imaging, targeted drug/gene delivery, and therapy. Nanocarriers, with the properties of smaller particle size, and long circulation time, would be advantageous in diagnostic and therapeutic applications. Nanocarriers can pass through blood capillary walls and cell membrane walls to deliver drugs. The mechanisms of interaction between ultrasound and nanocarriers are not clearly understood, which may be related to cavitation, mechanical effects, thermal effects, and so forth. These effects may induce transient membrane permeabilization (sonoporation) on a single cell level, cell death, and disruption of tissue structure, ensuring noninvasive, targeted, and efficient drug/gene delivery and therapy. The system has been used in various tissues and organs (in vitro or in vivo), including tumor tissues, kidney, cardiac, skeletal muscle, and vascular smooth muscle. In this review, we explore the research progress and application of ultrasound-mediated local drug/gene delivery with nanocarriers.

To determine reference values and tolerance limits of between-side differences for the calibers of the common femoral artery (CFA), superficial femoral artery (SFA), popliteal artery (PA), dorsalis pedis artery (DPA), and posterior tibial artery (PTA).

The study of the interaction of bubbles with shock waves and ultrasound is sometimes termed 'acoustic cavitation'. It is of importance in many biomedical applications where sound waves are applied. The use of shock waves and ultrasound in medical treatments is appealing because of their non-invasiveness. In this review, we present a variety of acoustics-bubble interactions, with a focus on shock wave-bubble interaction and bubble cloud phenomena. The dynamics of a single spherically oscillating bubble is rather well understood. However, when there is a nearby surface, the bubble often collapses non-spherically with a high-speed jet. The direction of the jet depends on the 'resistance' of the boundary: the bubble jets towards a rigid boundary, splits up near an elastic boundary, and jets away from a free surface. The presence of a shock wave complicates the bubble dynamics further. We shall discuss both experimental studies using high-speed photography and numerical simulations involving shock wave-bubble interaction. In biomedical applications, instead of a single bubble, often clouds of bubbles appear (consisting of many individual bubbles). The dynamics of such a bubble cloud is even more complex. We shall show some of the phenomena observed in a high-intensity focused ultrasound (HIFU) field. The nonlinear nature of the sound field and the complex inter-bubble interaction in a cloud present challenges to a comprehensive understanding of the physics of the bubble cloud in HIFU. We conclude the article with some comments on the challenges ahead.

Miridesap, a depleter of serum amyloid P component (SAP), forms an essential component of a novel approach to remove systemic amyloid deposits; low oral bioavailability necessitates that it is given parenterally. We sought to identify and clinically characterise a pro-drug that preserves the pharmacological properties of miridesap while having adequate oral bioavailability and physical stability.

Urinary tract infections (UTIs) caused by Escherichia coli create a large burden on healthcare and frequently lead to recurrent infections. Part of the success of E. coli as an uropathogenic bacterium can be attributed to its ability to form quiescent intracellular reservoirs in bladder cells and its persistence after antibiotic treatment. Cranberry juice and related products have been used for the prevention of UTIs with varying degrees of success. In this study, a group of cranberry pectic oligosaccharides (cPOS) were found to both inhibit quiescence and reduce the population of persister cells formed by the uropathogenic strain, CFT073. This is the first report detailing constituents of cranberry with the ability to modulate these important physiological aspects of uropathogenic E. coli. Further studies investigating cranberry should be keen to include oligosaccharides as part of the 'active' cocktail of chemical compounds.

The impact of ocean spray on the dynamics of the marine near-surface air boundary layer (MABL) in conditions of very high (hurricane) wind speeds is investigated. Toward this end, a model of the MABL in the presence of sea-spume droplets is developed. The model is based on the classical theory of the motion of suspended particles in a turbulent flow, where the mass concentration of droplets is not mandatory small. Description of the spume-droplet generation assumes that they, being torn off from breaking waves, are injected in the form of a jet of spray into the airflow at the altitude of breaking wave crests. The droplets affect the boundary-layer dynamics in two ways: via the direct impact of droplets on the airflow momentum forming the so-called spray force, and via the impact of droplets on the turbulent mixing through stratification. The latter is parametrized applying the Monin-Obukhov similarity theory. It is found that the dominant impact of droplets on the MABL dynamics appears through the action of the 'spray force' originated from the interaction of the 'rain of spray' with the wind velocity shear, while the efficiency of the stratification mechanism is weaker. The effect of spray leads to an increase in the wind velocity and suppression of the turbulent wind stress in the MABL. The key issue of the model is a proper description of the spume-droplet generation. It is shown that, after the spume-droplet generation is fitted to the observations, the MABL model is capable of reproducing the fundamental experimental finding-the suppression of the surface drag at very high wind speeds. We found that, at very high wind speeds, a thin part of the surface layer adjacent to the surface turns into regime of limited saturation with the spume droplets, resulting in the levelling off of the friction velocity and decrease of the drag coefficient as U(10)(-2), U(10) being the wind speed at 10-m height.

Biomedical ultrasound may induce adverse effects in patients by either thermal or non-thermal means. Temperatures above normal can adversely affect biological systems, but effects also may be produced without significant heating. Thermally induced teratogenesis has been demonstrated in many animal species as well as in a few controlled studies in humans. Various maximum 'safe' temperature elevations have been proposed, although the suggested values range from 0.0 to 2.5 degrees C. Factors relevant to thermal effects are considered, including the nature of the acoustic field in situ, the state of perfusion of the embryo/fetus, and the variation of sensitivity to thermal insult with gestational stage of development. Non-thermal mechanisms of action considered include acoustic cavitation, radiation force, and acoustic streaming. While cavitation can be quite destructive, it is extremely unlikely in the absence of stabilized gas bodies, and although the remaining mechanisms may occur in utero, they have not been shown to induce adverse effects. For example, pulsed, diagnostic ultrasound can increase fetal activity during exposure, apparently due to stimulation of auditory perception by radiation forces on the fetal head or auditory structures. In contrast, pulsed ultrasound also produces vascular damage near developing bone in the late-gestation mouse, but by a unknown mechanism and at levels above current US FDA output limits. It is concluded that: (1) thermal rather than nonthermal mechanisms are more likely to induce adverse effects in utero, and (2) while the probability of an adverse thermal event is usually small, under some conditions it can be disturbingly high.

A high-order accurate shock- and interface-capturing scheme is used to simulate the collapse of a gas bubble in water. In order to better understand the damage caused by collapsing bubbles, the dynamics of the shock-induced and Rayleigh collapse of a bubble near a planar rigid surface and in a free field are analysed. Collapse times, bubble displacements, interfacial velocities and surface pressures are quantified as a function of the pressure ratio driving the collapse and of the initial bubble stand-off distance from the wall; these quantities are compared to the available theory and experiments and show good agreement with the data for both the bubble dynamics and the propagation of the shock emitted upon the collapse. Non-spherical collapse involves the formation of a re-entrant jet directed towards the wall or in the direction of propagation of the incoming shock. In shock-induced collapse, very high jet velocities can be achieved, and the finite time for shock propagation through the bubble may be non-negligible compared to the collapse time for the pressure ratios of interest. Several types of shock waves are generated during the collapse, including precursor and water-hammer shocks that arise from the re-entrant jet formation and its impact upon the distal side of the bubble, respectively. The water-hammer shock can generate very high pressures on the wall, far exceeding those from the incident shock. The potential damage to the neighbouring surface is quantified by measuring the wall pressure. The range of stand-off distances and the surface area for which amplification of the incident shock due to bubble collapse occurs is determined.

We studied spark-generated cavitation bubbles inside water drops produced in microgravity. High-speed visualizations disclosed unique effects of the spherical and nearly isolated liquid volume. In particular, (1) toroidally collapsing bubbles generate two liquid jets escaping from the drop, and the "splash jet" discloses a remarkable broadening. (2) Shock waves induce a strong form of secondary cavitation due to the particular shock wave confinement. This feature offers a novel way to estimate integral shock wave energies in isolated volumes. (3) Bubble lifetimes in drops are shorter than in extended volumes in remarkable agreement with herein derived corrective terms for the Rayleigh-Plesset equation.

Cavitation and bubble dynamics have a wide range of practical applications in a range of disciplines, including hydraulic, mechanical and naval engineering, oil exploration, clinical medicine and sonochemistry. However, this paper focuses on how a fundamental concept, the Kelvin impulse, can provide practical insights into engineering and industrial design problems. The pathway is provided through physical insight, idealized experiments and enhancing the accuracy and interpretation of the computation. In 1966, Benjamin and Ellis made a number of important statements relating to the use of the Kelvin impulse in cavitation and bubble dynamics, one of these being 'One should always reason in terms of the Kelvin impulse, not in terms of the fluid momentum…'. We revisit part of this paper, developing the Kelvin impulse from first principles, using it, not only as a check on advanced computations (for which it was first used!), but also to provide greater physical insights into cavitation bubble dynamics near boundaries (rigid, potential free surface, two-fluid interface, flexible surface and axisymmetric stagnation point flow) and to provide predictions on different types of bubble collapse behaviour, later compared against experiments. The paper concludes with two recent studies involving (i) the direction of the jet formation in a cavitation bubble close to a rigid boundary in the presence of high-intensity ultrasound propagated parallel to the surface and (ii) the study of a 'paradigm bubble model' for the collapse of a translating spherical bubble, sometimes leading to a constant velocity high-speed jet, known as the Longuet-Higgins jet.

The scaling relations for bubbles induced by different external sources are investigated based on a modified Rayleigh model and experimental observations. The equations derived from the modified Rayleigh model are presented to describe the collapse of bubbles induced by the different external sources such as electrical spark, laser, and underwater explosion. A scaling law is then formulated to establish the scaling relations between the different types of bubbles. The scaling law reveals the fact that the characteristic length scale factor differs from the characteristic time scale factor for the different types of bubbles. It is then validated by our experimental observations of the spark- and laser-generated bubbles as well as the bubbles induced by underwater explosions from previous published reports. With the present scaling law, studies on spark- or laser-generated bubbles as well as their applications (for example, in industrial or biomedical related applications) can benefit from the experiences and information built up over the years in underwater explosion bubbles. Conversely, it is possible to substitute a spark- or laser-generated bubble for an underwater explosion bubble in the study of a large-scale and complex physical problem.

Active development of quantum informational components such as quantum computers and quantum key distribution systems requires parameter characterization of single photon detectors. A key property of the single photon detectors is detection efficiency. One of the methods of the detection efficiency measurement, as listed in the international standard ETSI, is the reference-free twin-photon-based Klyshko method. The signal-to-noise ratio (SNR) of this method depends on the combination of the pump wavelength, the nonlinear crystal's axis angle, and the type of detector's sensitive element. When the combination is difficult, one has to deal with the low SNR of the detector counts measurement. To gain the high SNR, one has to average the long record complicated with the "random telegraph signal" noise. This type of noise exhibits high spectral density at a zero frequency, where simple averaging works. The heterodyne based method we have proposed is to perform averaging at the higher frequency of the modulation introduced to the standard Klyshko measurement scheme. The method was numerically simulated and experimentally tested. The 14 times improvement in SNR for the proposed method relative to the simple averaging was demonstrated by the numerical simulation and confirmed experimentally.

Abstract

A boundary integral method is used to calculate the highly non-linear motion of both one and a vertical column of two bubbles beneath a free surface; although the theory is developed for a finite number of bubbles. Cubic splines are used to represent the surface of the bubble and the infinite free surface; with a non-linear distribution of nodes being employed on the free surface in order to more accurately capture the motion of the free surface spike, which experiments show to be narrow and pronounced when bubbles are generated close to the boundary. Calculations show excellent agreement with experiments in both the one- and two-bubble cases.

Carbon dioxide is Mars' primary atmospheric constituent and is an active driver of Martian surface evolution. CO₂ice sublimation mechanisms have been proposed for a host of features that form in the contemporary Martian climate. However, there has been very little experimental work or quantitative modelling to test the validity of these hypotheses. Here we present the results of the first laboratory experiments undertaken to investigate if the interaction between sublimating CO₂ice blocks and a warm, porous, mobile regolith can generate features similar in morphology to those forming on Martian dunes today. We find that CO₂sublimation can mobilise grains to form (i) pits and (ii) furrows. We have documented new detached pits at the termini of linear gullies on Martian dunes. Based on their geomorphic similarity to the features observed in our laboratory experiments, and on scaling arguments, we propose a new hypothesis that detached pits are formed by the impact of granular jets generated by sublimating CO₂. We also study the erosion patterns formed underneath a sublimating block of CO₂ice and demonstrate that these resemble furrow patterns on Mars, suggesting similar formation mechanisms.

After a bubble bursts at a liquid surface, the collapse of the cavity generates capillary waves, which focus on the axis of symmetry to produce a jet. The cavity and jet dynamics are primarily controlled by a nondimensional number that compares capillary inertia and viscous forces, i.e., the Laplace number La=ργR_{0}/μ^{2}, where ρ, μ, γ, and R_{0} are the liquid density, viscosity, interfacial tension, and the initial bubble radius, respectively. In this Letter, we show that the time-dependent profiles of cavity collapse (t<t_{0}) and jet formation (t>t_{0}) both obey a |t-t_{0}|^{2/3} inviscid scaling, which results from a balance between surface tension and inertia forces. Moreover, we present a scaling law, valid above a critical Laplace number, which reconciles the time-dependent scaling with the recent scaling theory that links the Laplace number to the final jet velocity and ejected droplet size. This leads to a self-similar formula which describes the history of the jetting process, from cavity collapse to droplet formation.

The collapse of a bubble of radius R_{o} at the surface of a liquid generating a liquid jet and a subsequent first drop of radius R is universally scaled using the Ohnesorge number Oh=μ/(ρσR_{o})^{1/2} and a critical value Oh^{*} below which no droplet is ejected; ρ, σ, and μ are the liquid density, surface tension, and viscosity, respectively. First, a flow field analysis at ejection yields the scaling of R with the jet velocity V as R/l_{μ}∼(V/V_{μ})^{-5/3}, where l_{μ}=μ^{2}/(ρσ) and V_{μ}=σ/μ. This resolves the scaling problem of curvature reversal, a prelude to jet formation. In addition, the energy necessary for the ejection of a jet with a volume and averaged velocity proportional to R_{o}R^{2} and V, respectively, comes from the energy excess from the total available surface energy, proportional to σR_{o}^{2}, minus the one dissipated by viscosity, proportional to μ(σR_{o}^{3}/ρ)^{1/2}. Using the scaling variable φ=(Oh^{*}-Oh)Oh^{-2}, it yields V/V_{μ}=k_{v}φ^{-3/4} and R/l_{μ}=k_{d}φ^{5/4}, which collapse published data since 1954 and resolve the scaling of R and V with k_{v}=16, k_{d}=0.6, and Oh^{*}=0.043 when gravity effects are negligible.

This corrects the article DOI: 10.1103/PhysRevLett.118.221101.

This work examines the ejection of droplets from a bursting gas bubble on a free liquid surface, both experimentally and numerically. We explore the physical processes which govern the bursting of bubbles and the subsequent formation of "jet" droplets. We present new relationships regarding the dependence of jet drop formation on bubble diameter. Furthermore, we propose a new dimensionless parameter to describe the region of properties where "jet" drops will occur. This parameter, termed the droplet number ( Dn), complements existing parameters defining jet drop formation, namely, a maximum Ohnesorge number and a maximum Bond number.

Finite-time singularities--local divergences in the amplitude or gradient of a physical observable at a particular time--occur in a diverse range of physical systems. Examples include singularities capable of damaging optical fibres and lasers in nonlinear optical systems, and gravitational singularities associated with black holes. In fluid systems, the formation of finite-time singularities cause spray and air-bubble entrainment, processes which influence air-sea interaction on a global scale. Singularities driven by surface tension have been studied in the break-up of pendant drops and liquid sheets. Here we report a theoretical and experimental study of the generation of a singularity by inertial focusing, in which no break-up of the fluid surface occurs. Inertial forces cause a collapse of the surface that leads to jet formation; our analysis, which includes surface tension effects, predicts that the surface profiles should be describable by a single universal exponent. These theoretical predictions correlate closely with our experimental measurements of a collapsing surface singularity. The solution can be generalized to apply to a broad class of singular phenomena.

We study a type Ia supernova explosion using three-dimensional numerical simulations based on reactive fluid dynamics. We consider a delayed-detonation model that assumes a deflagration-to-detonation transition. In contrast with the pure deflagration model, the delayed-detonation model releases enough energy to account for a healthy explosion, and does not leave carbon, oxygen, and intermediate-mass elements in central parts of a white dwarf. This removes the key disagreement between simulations and observations, and makes a delayed detonation the mostly likely mechanism for type Ia supernovae.

This study explores the properties of spherical combustion clouds in explosions. Two cases are investigated: (1) detonation of a TNT charge and combustion of its detonation products with air, and (2) shock dispersion of aluminum powder and its combustion with air. The evolution of the blast wave and ensuing combustion cloud dynamics are studied via numerical simulations with our adaptive mesh refinement combustion code. The code solves the multi-phase conservation laws for a dilute heterogeneous continuum as formulated by Nigmatulin. Single-phase combustion (e.g., TNT with air) is modeled in the fast-chemistry limit. Two-phase combustion (e.g., Al powder with air) uses an induction time model based on Arrhenius fits to Boiko’s shock tube data, along with an ignition temperature criterion based on fits to Gurevich’s data, and an ignition probability model that accounts for multi-particle effects on cloud ignition. Equations of state are based on polynomial fits to thermodynamic calculations with the Cheetah code, assuming frozen reactants and equilibrium products. Adaptive mesh refinement is used to resolve thin reaction zones and capture the energy-bearing scales of turbulence on the computational mesh (ILES approach). Taking advantage of the symmetry of the problem, azimuthal averaging was used to extract the mean and rms fluctuations from the numerical solution, including: thermodynamic profiles, kinematic profiles, and reaction-zone profiles across the combustion cloud. Fuel consumption was limited to$\sim $60–70 %, due to the limited amount of air a spherical combustion cloud can entrain before the turbulent velocity field decays away. Turbulent kinetic energy spectra of the solution were found to have both rotational and dilatational components, due to compressibility effects. The dilatational component was typically about 1 % of the rotational component; both seemed to preserve their spectra as they decayed. Kinetic energy of the blast wave decayed due to the pressure field. Turbulent kinetic energy of the combustion cloud decayed due to enstrophy$\overline{\omega ^{2}} $and dilatation$\overline{\Delta ^{2}} $.

This Letter presents first experimental results of the laser imprint reduction in fusion scale plasmas using a low-density foam layer. The experiments were conducted on the LIL facility at the energy level of 12 kJ with millimeter-size plasmas, reproducing the conditions of the initial interaction phase in the direct-drive scheme. The results include the generation of a supersonic ionization wave in the foam and the reduction of the initial laser fluctuations after propagation through 500 mum of foam with limited levels of stimulated Brillouin and Raman scattering. The smoothing mechanisms are analyzed and explained.

The fluid dynamic interaction of cavitation bubbles with adherent cells on a substrate is experimentally investigated. We find that the nonspherical collapse of bubbles near to the boundary is responsible for cell detachment. High-speed photography reveals that a wall bounded flow leads to the detachment of cells. Cells at the edge of the circular area of detachment are found to be permanently porated, whereas cells at some distance from the detachment area undergo viable cell membrane poration (sonoporation). The wall flow field leading to cell detachment is modeled with a self-similar solution for a wall jet, together with a kinetic ansatz of adhesive bond rupture. The self-similar solution for the delta-type wall jet compares very well with the full solution of the Navier-Stokes equation for a jet of finite thickness. Apart from annular sites of sonoporation we also find more homogenous patterns of molecule delivery with no cell detachment.

Cavitation bubbles collapsing and rebounding in a pressure gradient ∇p form a "microjet" enveloped by a "vapor jet." This Letter presents unprecedented observations of the vapor jets formed in a uniform gravity-induced ∇p, modulated aboard parabolic flights. The data uncover that the normalized jet volume is independent of the liquid density and viscosity and proportional to ζ ≡ |∇p|R(0)/Δp, where R(0) the maximal bubble radius and Δp is the driving pressure. A derivation inspired by "Kelvin-Blake" considerations confirms this law and reveals its negligible dependence of surface tension. We further conjecture that the jet only pierces the bubble boundary if ζ ≳ 4 × 10(-4).

Numerical simulations of bubble pulsation and sonoluminescence (SL) have been performed for helium or xenon bubbles in mercury and water under the experimental conditions of Futakawa et al. [M. Futakawa, T. Naoe, and M. Kawai, in Nonlinear Acoustics-Fundamentals and Applications: 18th International Symposium on Nonlinear Acoustics (ISNA 18), AIP Conf. Proc. No. 1022, edited by B. O. Enflo, C. M. Hedberg, and L. Kari (AIP, New York, 2008), p. 197]. The results of the numerical simulations have revealed that the bubble expansion is much larger in water than in mercury mainly because the density of water is one order of magnitude smaller than that of mercury. The SL intensity is higher in water than that in mercury although the maximum bubble temperature is lower. This is caused by the much larger amount of vapor inside a bubble as the saturated vapor pressure of water is four orders of magnitude larger than that of mercury at room temperature. The SL intensity from xenon is much larger than that from helium due both to lower ionization potential and higher bubble temperature due to lower thermal conductivity. The instantaneous SL power may be as large as 200 W from xenon in water. The maximum temperature inside a xenon bubble in mercury may be as high as about 80 000 K. It is suggested that the maximum pressure in mercury due to shock waves emitted from bubbles increases as the SL intensity increases, although they are not simply correlated in water because the amount of water vapor trapped inside a bubble influences the SL intensity in a complex way.

A high-order accurate shock- and interface-capturing scheme is used to simulate the collapse of a gas bubble in water. In order to better understand the damage caused by collapsing bubbles, the dynamics of the shock-induced and Rayleigh collapse of a bubble near a planar rigid surface and in a free field are analysed. Collapse times, bubble displacements, interfacial velocities and surface pressures are quantified as a function of the pressure ratio driving the collapse and of the initial bubble stand-off distance from the wall; these quantities are compared to the available theory and experiments and show good agreement with the data for both the bubble dynamics and the propagation of the shock emitted upon the collapse. Non-spherical collapse involves the formation of a re-entrant jet directed towards the wall or in the direction of propagation of the incoming shock. In shock-induced collapse, very high jet velocities can be achieved, and the finite time for shock propagation through the bubble may be non-negligible compared to the collapse time for the pressure ratios of interest. Several types of shock waves are generated during the collapse, including precursor and water-hammer shocks that arise from the re-entrant jet formation and its impact upon the distal side of the bubble, respectively. The water-hammer shock can generate very high pressures on the wall, far exceeding those from the incident shock. The potential damage to the neighbouring surface is quantified by measuring the wall pressure. The range of stand-off distances and the surface area for which amplification of the incident shock due to bubble collapse occurs is determined.

Spherically collapsing cavitation bubbles produce a shock wave followed by a rebound bubble. Here we present a systematic investigation of the energy partition between the rebound and the shock. Highly spherical cavitation bubbles are produced in microgravity, which suppresses the buoyant pressure gradient that otherwise deteriorates the sphericity of the bubbles. We measure the radius of the rebound bubble and estimate the shock energy as a function of the initial bubble radius (2-5.6mm) and the liquid pressure (10-80kPa). Those measurements uncover a systematic pressure dependence of the energy partition between rebound and shock. We demonstrate that these observations agree with a physical model relying on a first-order approximation of the liquid compressibility and an adiabatic treatment of the noncondensable gas inside the bubble. Using this model we find that the energy partition between rebound and shock is dictated by a single nondimensional parameter ξ=Δpγ6/[p(g0)1/γ(ρc2)1-1/γ], where Δp=p∞ - pv is the driving pressure, p∞ is the static pressure in the liquid, pv is the vapor pressure, pg0 is the pressure of the noncondensable gas at the maximal bubble radius, γ is the adiabatic index of the noncondensable gas, ρ is the liquid density, and c is the speed of sound in the liquid.

The dynamics of a water jet on a flat free surface are investigated using a nanosecond pulsed laser for creating an oscillating bubble with different depths beneath the free surface. A thin jet is shown to deform a crater surface resulted from surface depression and cause a circular ring-shaped crater on the connection surface between the crater of surface depression and the thin jet. The collapse of this circular ring-shaped crater is proposed to the crown-like formation around a thick jet. The evolution of the bubble depth suggests a classification of four distinctive ranges of the bubble depths: non-crown formation when the parameter of bubble depth over the maximum bubble radius gamma <= 0.5, unstable crown formation when 0.5 <= gamma <= 0.6, crown-like structure with a complete crown wall when 0.6 <= gamma <= 1.1, and non-crown formation when 1.1 <= gamma. Furthermore, the orientation of the crown wall gradually turns counterclockwise to vertical direction with increasing gamma from 0.5 to 1.1, implying a high correlation between the orientation of the crown wall and the depth of the bubble. This correlation is explained and discussed by the directional change of the jet eruption from the collapse of circular ring-shaped crater. (C)2013 Optical Society of America

The efficiency of spin polarized charge transfer was investigated in an Fe/MgO tunnel barrier/GaAs based structure using spin dependent photocurrent measurements, whereby a spin imbalance in carrier population was generated in the GaAs by circularly polarized light. The dominance of tunneling transport processes over Schottky emission gave rise to a high spin transfer efficiency of 35% under the photovoltaic mode of device operation. A spin dependent tunneling conductance associated with spin polarized electron transport was identified by the observation of phase changes. This transport prevails over the unpolarized electron and hole conduction over the bias range which corresponds to flat band conditions.

Transverse acoustic (TA) excitation modes were observed in inelastic x-ray scattering (IXS) spectra of liquid Sn. The excitation energies and widths of the TA modes are in good agreement with results of an ab initio molecular dynamics simulation. By comparing current correlation spectra between the experimental and theoretical results quantitatively, we have concluded that the TA modes can be detected experimentally through the quasi-TA branches in the longitudinal current correlation spectra. The lifetime and propagation length of the TA modes were determined to be ~0.7 ps and 0.8-1.0 nm, respectively, corresponding to the size of cages formed instantaneously in liquid Sn.

A laser-based technique for printing transparent and weakly absorbing liquids is developed. Its principle of operation relies in the tight focusing of short laser pulses inside the liquid and close to its free surface, in such a way that the laser radiation is absorbed in a tiny volume around the beam waist, with practically no absorption in any other location along the beam path. If the absorbed energy overcomes the optical breakdown threshold, a cavitation bubble is generated, and its expansion results in the propulsion of a small fraction of liquid which can be collected on a substrate, leading to the printing of a microdroplet for each laser pulse. The technique does not require the preparation of the liquid in thin film form, and its forward mode of operation imposes no restriction concerning the optical properties of the substrate. These characteristics make it well suited for printing a wide variety of materials of interest in diverse applications. We demonstrate that the film-free laser forward printing technique is capable of printing microdroplets with good resolution, reproducibility and control, and analyze the influence of the main process parameter, laser pulse energy. The mechanisms of liquid printing are also investigated: time-resolved imaging provides a clear picture of the dynamics of liquid transfer which allows understanding the main features observed in the printed droplets.

The basic principle and numerical technique for simulating two three-dimensional bubbles near a free surface are studied in detail by using boundary element method. The singularities of influence coefficient matrix are eliminated using coordinate transformation and so-called 4πrule. The solid angle for the open surface is treated in direct method based on its definition. Several kinds of configurations for the bubbles and free surface have been investigated. The pressure contours during the evolution of bubbles are obtained in our model and can better illuminate the mechanism underlying the motions of bubbles and free surface. The bubble dynamics and their interactions have close relation with the standoff distances, buoyancy parameters and initial sizes of bubbles. Completely different bubble shapes, free surface motions, jetting patterns and pressure distributions under different parameters can be observed in our model, as demonstrated in our calculation results.

The present study numerically investigates liquid-jet characteristics of acoustic cavitation during emulsification in water/gallium/air and water/silicone oil/air systems. It is found that a high-speed liquid jet is generated when acoustic cavitation occurs near a minute droplet of one liquid in another. The velocity of liquid jet significantly depends on the ultrasonic pressure monotonically increasing as the pressure amplitude increases. Also, the initial distance between cavitation bubble and liquid droplet affects the jet velocity significantly. The results revealed that the velocity takes maximum values when the initial distance between the droplet and cavitation bubble is moderate. Surprisingly, the liquid jet direction was found to depend on the droplet properties. Specifically, the direction of liquid jet is toward the droplet in the case of water/gallium/air system, and vice versa the jet is directed from the droplet in the case of water/silicone oil/air system. The jet directionality can be explained by location of the high-pressure spot generated during the bubble contraction.

A high-velocity fluid stream ejected from an orifice or nozzle is a common mechanism to produce liquid jets in inkjet printers or to produce sprays among other applications. In the present research, we show the generation of liquid jets of controllable direction produced within a sessile water droplet by thermocavitation. The jets are driven by an acoustic shock wave emitted by the collapse of a hemispherical vapor bubble at the liquid-solid/substrate interface. The generated shock wave is reflected at the liquid-air interface due to acoustic impedance mismatch generating multiple reflections inside the droplet. During each reflection, a force is exerted on the interface driving the jets. Depending on the position of the generation of the bubble within the droplet, the mechanical energy of the shock wave is focused on different regions at the liquid-air interface, ejecting cylindrical liquid jets at different angles. The ejected jet angle dependence is explained by a simple ray tracing model of the propagation of the acoustic shock wave inside the droplet.